Santa Cruz de la Sierra Vacations from $1,200

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The Latest Santa Cruz de la Sierra vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza España

Hotel Riu Plaza España

4 out of 5
Madrid Centro
Price was $1,638, price is now $1,200 per person
$1,200
per person
Jul 23 - Jul 27
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Madrid (MAD)
9.4/10 Exceptional! (4,810 reviews)
Breakfast was great. Salad, fruit, eggs, was what i ate but they had meat, cheese, beans. Fresh and delicious. I looked forward to breakfast every morning. Service was efficient

Reviewed on May 7, 2026

Gran Hotel Inglés - The Leading Hotels of the World

Gran Hotel Inglés - The Leading Hotels of the World

5 out of 5
Madrid Centro
Save 100% on your flight
Price was $3,631, price is now $2,490 per person
$2,490
per person
Jun 15 - Jun 21
found 1 day ago
Roundtrip flight included
New York (JFK) to Madrid (MAD)
10/10 Exceptional! (472 reviews)
Property is nice, but old and not that renovated location is good but not great, service is also good but not great

Reviewed on Apr 30, 2026

Casa Faraona Luxury Residences

Casa Faraona Luxury Residences

4 out of 5
Salamanca
Save 100% on your flight
Price was $2,582, price is now $1,783 per person
$1,783
per person
Jul 23 - Jul 27
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Madrid (MAD)
9.6/10 Exceptional! (46 reviews)
Spatious, modern and elegant with an excellent location.

Reviewed on Apr 10, 2026

Main Street Madrid

Main Street Madrid

3 out of 5
Madrid Centro
Price was $1,879, price is now $1,305 per person
$1,305
per person
Jun 9 - Jun 13
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Madrid (MAD)
8.6/10 Excellent! (261 reviews)
Very nice hotel and staff. It was a bit hard to find so that’s why I rated it 4 instead of 5 stars. It’s on the 5th floor btw. Also the bathroom smelled like sewage a few times coming from the drain, but it cleared on its own. Great location also!

Reviewed on Apr 29, 2026

Relais & Châteaux Heritage Madrid

Relais & Châteaux Heritage Madrid

5 out of 5
Salamanca
Price was $2,116, price is now $1,553 per person
$1,553
per person
Jul 23 - Jul 27
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Madrid (MAD)
9.6/10 Exceptional! (582 reviews)
it was expensive, 30 euros per person

Reviewed on Mar 29, 2026

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Santa Cruz de la Sierra Hotel Deals

Rural house (full rental) El Olivar del Marqués for 26 people

Rural house (full rental) El Olivar del Marqués for 26 people

Santa Cruz de la Sierra Cáceres
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Rural house (full rental) El Olivar del Marqués for 26 people
Parador de Trujillo

Parador de Trujillo

4 out of 5
Santa Beatriz de Silva 1 Trujillo Caceres
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $100 total per night from May 24 to May 25
$100 total
May 24 - May 25
Total with taxes and fees
9.2/10 Wonderful! (229 reviews)
Magnifique , très bien situé et très bien équipé , tout était parfait ; juste prévoir peut être des chaînes de Tv pour les etrangers

Reviewed on May 7, 2026

Parador de Trujillo
Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta

4 out of 5
Calle Ballesteros 6 Trujillo Caceres
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $84 total per night from Jun 7 to Jun 8
$84 total
Jun 7 - Jun 8
Total with taxes and fees
9.2/10 Wonderful! (340 reviews)
Wonderful location. Friendly staff.

Reviewed on Mar 28, 2026

Eurostars Palacio Santa Marta
See all 87 properties in Santa Cruz de la Sierra
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Cruz de la Sierra Vacation Packages

Santa Cruz de la Sierra Essential Information

Language
Spanish
Currency
Euros
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
310
Max Temp Winter
55ºF
Max Temp Summer
90ºF
Top Sights
Trujillo Castle, Juan Pizarro de Orellana Palace and Palace of the Marquis of the Conquest

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Frequently asked questions

How much does a Santa Cruz de la Sierra vacation package cost?
You can snap up a vacation package to this top destination from $1,200 on Expedia. However, how much your vacation to Santa Cruz de la Sierra costs will depend on factors like your hotel choice, season and length of stay.
What are the cheapest months to go to Santa Cruz de la Sierra?
February, November and December are great times to look for cheap Santa Cruz de la Sierra vacation packages. Opting to travel in quieter months means you'll typically find reduced prices on flights and hotels.
How many days is enough for Santa Cruz de la Sierra?
The ideal length of your Santa Cruz de la Sierra vacation depends on what you'd like to do and see. Generally, a handful of days to a week will give you plenty of time to go to all the leading sights and explore some hidden spots along the way.
How to find the best Santa Cruz de la Sierra package deals?
Use Expedia's filters to find some of the best Santa Cruz de la Sierra package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your adventure for midweek, or search for Santa Cruz de la Sierra package deals in the low season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package as soon as possible.
Is it cheaper to book a Santa Cruz de la Sierra vacation as a package?
An Expedia vacation package could land you great savings when compared to arranging hotels and flights separately. Better still, you can customize your Santa Cruz de la Sierra getaway to fit your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
When to book a vacation package to Santa Cruz de la Sierra?
If you're planning a spontaneous Santa Cruz de la Sierra getaway, browse our last-minute deals that can be booked up to one week before you take off. Don't want to leave things to the last minute? You can find incredible deals on your hotels and flights by booking ahead.
Does Expedia offer Book Now, Pay Later Santa Cruz de la Sierra vacation packages?
If you're like us, you love going away but don't love the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the total cost of your Santa Cruz de la Sierra vacation across 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.