Santa Cruz de la Sierra Vacations from $797
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The Latest Santa Cruz de la Sierra vacation packages
Price found within the past 48 hours. Click for updated prices.
Hotel Atlantico Madrid
Madrid Centro
$797
per person
Dec 10 - Dec 15
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Madrid (MAD)
9.8/10 Exceptional! (2,143 reviews)
The room was well-appointed and the fully-tiled bathroom was beautiful—with a double sink, a large and fast-filling tub with separate controls for overhead shower and hose heads, plus separate WC with a bidet. Views of Gran Via from the dining room were amazing and the views from the terraces were beyond amazing. There is a small bar at the terrace level with three or four separate comfortable indoor spaces for afternoon coffee or cocktails if the terraces are too chilly.
Central location is busy (think Times Square, with iconic Schweppes building as the Jumbotron) with super-easy access to multiple (3?) Metro lines. The staff was very friendly and accommodating. We would highly recommend this hotel!!
Reviewed on Oct 22, 2026
Hotel Exe Moncloa
Chamberí
$1,207
per person
Nov 25 - Dec 1
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Madrid (MAD)
8.2/10 Very Good! (996 reviews)
Rooftop pool was "closed for the season" even though it was 30degC outside in September. Really???Location was great, directly across from Moncloa Metro station. Staff pleasant.
Reviewed on Sep 29, 2026
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Rural house (full rental) El Olivar del Marqués for 26 people
Santa Cruz de la Sierra Cáceres
Eurostars Palacio Santa Marta
Calle Ballesteros 6 Trujillo Caceres
Fully refundableReserve now, pay when you stay
$60 nightly
$66 total
Nov 22 - Nov 23
Total with taxes and fees
Parador de Trujillo
Santa Beatriz de Silva 1 Trujillo Caceres
Fully refundableReserve now, pay when you stay
$73 nightly
$81 total
Nov 3 - Nov 4
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Santa Cruz de la Sierra Essential Information
Language | Spanish |
|---|---|
Currency | Euros |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Population | 310 |
Max Temp Winter | 55ºF |
Max Temp Summer | 90ºF |
Top Sights | Trujillo Castle, Juan Pizarro de Orellana Palace and Palace of the Marquis of the Conquest |
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Frequently asked questions
How much does a Santa Cruz de la Sierra vacation package cost?
You can snap up a vacation package to this top destination from $797 on Expedia. However, how much your vacation to Santa Cruz de la Sierra costs will depend on factors like your hotel choice, season and length of stay.
What are the cheapest months to go to Santa Cruz de la Sierra?
February, November and December are great times to look for cheap Santa Cruz de la Sierra vacation packages. Opting to travel in quieter months means you'll typically find reduced prices on flights and hotels.
How many days is enough for Santa Cruz de la Sierra?
The ideal length of your Santa Cruz de la Sierra vacation depends on what you'd like to do and see. Generally, a handful of days to a week will give you plenty of time to go to all the leading sights and explore some hidden spots along the way.
How to find the best Santa Cruz de la Sierra package deals?
Use Expedia's filters to find some of the best Santa Cruz de la Sierra package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your adventure for midweek, or search for Santa Cruz de la Sierra package deals in the low season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package as soon as possible.
Is it cheaper to book a Santa Cruz de la Sierra vacation as a package?
An Expedia vacation package could land you great savings when compared to arranging hotels and flights separately. Better still, you can customize your Santa Cruz de la Sierra getaway to fit your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
When to book a vacation package to Santa Cruz de la Sierra?
If you're planning a spontaneous Santa Cruz de la Sierra getaway, browse our last-minute deals that can be booked up to one week before you take off. Don't want to leave things to the last minute? You can find incredible deals on your hotels and flights by booking ahead.
Does Expedia offer Book Now, Pay Later Santa Cruz de la Sierra vacation packages?
If you're like us, you love going away but don't love the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the total cost of your Santa Cruz de la Sierra vacation across 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.
Explore a world of travel with Expedia
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- Trujillo Castle
- Pizarro House Museum
- Church of Santa Maria la Mayor Trujillo
- Palacio de la Conquista
- Visit Herguijuela
- Juan Pizarro de Orellana Palace
- Visit Montanchez
- Visit Torrequemada
- San Martin Church
- Visit Trujillo
- Visit Berzocana
- Visit Madrigalejo
- Visit Arroyomolinos de Montanchez
- Iglesia San Juan Bautista
- Visit Garciaz
- Visit Plasenzuela
- Plaza Mayor
- Visit Santa Marta de Magasca
- Visit Madronera
- Visit Logrosan
- Visit Miajadas
- Palace of the Dukes of San Carlos
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.